Failure of ketamine to interact with opiate receptors
摘要：
Ketamine, an anesthetic agent endowed with several morphine-like effects, failed to displace 3H-dihydromorphine or 3H-methionine-enkephalin from opiate receptors in the rat brain synaptosomal-mitochondrial membrane preparations. Furthermore, ketamine-induced analgesia in rats was not antagonized by naloxone, suggesting that this effect is not mediated by opiate receptors.
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DOI：
10.1016/0014-2999(80)90079-5
被引量：
年份：
1980
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