Heterocyclic thiosemicarbazones: correlation between structure, inhibition of ribonucleotide reductase, and inhibition of DNA viruses.
摘要：
The authors have compared the antiviral activity of a number of heterocyclic thiosemicarbazones with their ability to inhibit ribonucleotide reductase. A preparation of the enzyme was made from normal HEp-2 cells, and its activity was determined by a method based on the conversion of labelled cyti-dine diphosphate to its deoxy analogue. The thiosemicarbazones of 2-formylpyridine, 5-hydroxy-2-fo...
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DOI：
10.3181/00379727-133-34528
被引量：
年份：
1970
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