Parallel kinetic resolution of an oxazolidinone using a quasi-enantiomeric combination of [D,13C]-isotopomers of pentafluorophenyl 2-phenyl propionate
摘要:
Parallel kinetic resolution of Evans' phenylglycine derived oxazolidinone using an equimolar combination of quasi-enantiomeric active esters (derived from [D,13C]-labeled 2-phenylpropionic acid) was achieved. The levels of stereocontrol were high, leading to products with predictable configurations. Chirality, 2007. © 2007 Wiley-Liss, Inc.
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关键词:
chiral auxiliaries chiral resolution evans oxazolidinones kinetic resolution molecular recognition profens stereoselectivity
DOI:
10.1002/chir.20367
被引量:
年份:
2007
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