Building a new conceptual framework for receptor heteromers
摘要：
Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.
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关键词：
PROTEIN-COUPLED RECEPTORS INTERNATIONAL UNION PHARMACOLOGY RELEVANCE HETERODIMERIZATION CLASSIFICATION IDENTIFICATION NOMENCLATURE MODULATION STRIATUM
DOI：
10.1038/nchembio0309-131
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