Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000.
摘要：
Four 3″- and 4″-deoxy and -fluorogalactosyl ceramides were synthesized, and their ability to stimulate iNKT cells, based on levels of IL-2 production, was assessed in three NKT cell receptor hybridomas. In two of the hybridomas, 1.2 and 2H4, all of the analogs were immunostimulatory, while in the 1.4 hybridoma only the 4″-fluoro analog led to the production of significant levels of IL-2.Graphical abstract
展开
关键词：
DOI：
10.1016/j.bmcl.2009.06.005
被引量：
年份：
2009
Elsevier
(全网免费下载)
Elsevier
国家科技图书文献中心
(权威机构)
Semantic Scholar
掌桥科研
查看更多
dx.doi.org
Europe PMC
(全网免费下载)
NCBI
Pubmed Central
(全网免费下载)
NCBI
NCBI
(全网免费下载)
Europe PMC
ResearchGate
(全网免费下载)
ResearchGate
EBSCO
EBSCO
leaddiscovery.co.uk
www.socolar.com
frontiersin.org
pubfacts.com
mysciencework.com
学术范
学术范
(全网免费下载)
mendeley.com
pubget.com
pherobase.com
deepdyve.com
onAcademic
Elsevier
(全网免费下载)
NCBI
(全网免费下载)
Europe PMC
(全网免费下载)
Pubmed Central
(全网免费下载)
ResearchGate
(全网免费下载)
学术范
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
