Regulation of Lipoprotein Assembly, Secretion and Fatty Acid β-Oxidation by Krüppel-Like Transcription Factor, klf-3
摘要：
Mammals regulate lipid secretion and distribution to maintain normal levels of TG in adipocytes.Mutation in klf-3 reduces the number of mitochondria probably leading to lower β-oxidation.Vitamin D increases fat levels in klf-3 mutant by lowering the rate of β-oxidation.klf-3 may have an important role in regulating lipid assembly and secretion.We establish that klf-3 controls lipid storage, secretion and mitochondrial proliferation.
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DOI：
10.1016/j.jmb.2013.04.020
被引量：
年份：
2013
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