The Role of Baroreceptors in the Cardiovascular Response to Ketamine
摘要：
To elucidate the role of the intravascular baroreceptors in the cardiovascular stimulation associated with ketamine anesthesia, an experiment was devised in which the proposed inhibitory baroreceptor mechanism could be effectively blacked by carotid sinus nerve stimulation. In neurologically intact dogs which responded normally to ketamine before and after carotid sinus nerve stimulation, the cardiovascular effect of the drug was not altered by baroreceptor nerve stimulation. In light of this finding and those of other workers, the cardiovascular response to ketamine anesthesia most likely originates at some site in the central nervous system or at a peripheral sensor other than the baroreceptors.
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DOI：
10.1213/00000539-197409000-00015
被引量：
年份：
1974
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