The Origin of Membrane Bioenergetics
摘要：
Harnessing energy as ion gradients across membranes is as universal as the genetic code. We leverage new insights into anaerobe metabolism to propose geochemical origins that account for the ubiquity of chemiosmotic coupling, and Na+/H+ transporters in particular. Natural proton gradients acting across thin FeS walls within alkaline hydrothermal vents could drive carbon assimilation, leading to the emergence of protocells within vent pores. Protocell membranes that were initially leaky would eventually become less permeable, forcing cells dependent on natural H+ gradients to pump Na+ ions. Our hypothesis accounts for the Na+/H+ promiscuity of bioenergetic proteins, as well as the deep divergence between bacteria and archaea.
展开
DOI：
10.1016/j.cell.2012.11.050
被引量：
年份：
2012
Elsevier
国家科技图书文献中心
(权威机构)
万方医学
dx.doi.org
www.ingentaconnect.com
查看更多
NCBI
Cell Press
Cell Press
(全网免费下载)
Europe PMC
NCBI
AGRIS
ResearchGate
EBSCO
advances.sciencemag.org
学术范
rstb.royalsocietypublishing.org
advan.physiology.org
mendeley.com
bvsalud.org
pubfacts.com
mysciencework.com
eprints.ucl.ac.uk
onAcademic
scienceopen.com
nick-lane.net
(全网免费下载)
学术范
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
