Inactivation of the p34cdc2-cyclin B complex by the human wee1 tyrosine kinase.
摘要:
Examines the mechanisms that regulate progression through the eukaryotic cell cycle. Regulation of entry into mitosis in Schizosaccharomyces pombe by the wee1+ gene; Encoding a protein kinase with serine-. theonine-, and tyrosine-phosphorylating activities; Wee1+ kinase negatively regulating mitosis by phosphorylating p34cdc2 on tyrosine 15, thereby inactivating the p34cdc2-cyclin B complex.
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年份:
1992
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