摘要：

The products of the enzymatic separation of yeast ribonucleic acid by crystalline ribonuclease have been analyzed by ion exchange and paper chromatography. The mononucleotide product is almost exclusively uridylic and cytidylic acids in approximately equal amounts. The small quantity of adenylic and guanylic acid appearing as mononucleotides seems to arise from higher molecular weight compounds during the analytical separation on the ion-exchange resin. Several discrete fractions, which were bound more strongly to the anion exchanger than are mononucleotides, were analyzed and each was found to have a different polynucleotide composition. These latter fractions may be artifacts resulting from the analytical procedure or polynucleotide subgroups arising from the action of nuclease on nucleic acid or degradation products of such polynucleotides.

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