Molecular Approaches to Population Biology
摘要：
Population biologists adopted protein electrophoresis to measure genetic variation in the 1960s and, more recently, have adopted a variety of techniques to detect variation in DNA sequences directly. In comparison to protein polymorphisms, DNA markers reveal more genetic variation, and provide population biologists with choices among sets of loci with different patterns of inheritance. Use of both protein polymorphisms and organellar genomes has dramatically increased the ability to detect patterns of mating in hybrid zones. The use of both proteins and DNA markers has also produced some intriguing puzzles; patterns of geographic variation and inferences of gene flow differ dramatically between these sets of loci, and nuclear markers may not show the correlations between heterozygosity and components of fitness that have been reported for protein polymorphisms.
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DOI：
10.1146/annurev.ecolsys.25.1.45
被引量：
年份：
1994
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