摘要：

The specific retention volumes of several low molecular weight alcohols in a liquid-liquid chromatography (LLC) system using glycerol as the stationary phase and n-heptane mobile phase are analyzed in terms of a thermodynamic theory of solute retention previously proposed. An initial evaluation is made of the effect on retention measurements of eluent flow rate, sample size, solute interactions, liquid loading, and solid support. Infinite dilution activity coefficients for the alcohols in glycerol are derived from retention data obtained over a range of temperatures from 25° to 45° C. From these data, partial molar Gibbs free energies and partial molar excess enthalpies and entropies of mixing are calculated. A complete LLC apparatus based on a gas chromatographic analog is described, and the comparison between the two chromatographic techniques is emphasized.

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