Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the ...
NP Desai，P Soon-Shiong，S Magdasi，... - EP
Kinesin inhibitors as cancer therapeutics
The invention provides novel compounds having a substituted imidazole ring, and methods of using such compounds for the treatment of certain disorders such as hematological cancers and solid tumors. The compounds of the invention are tri...
T Abrams，Barsanti, Paul A.，D Duhl，... - US
NON-REPLICATING PROBIOTIC MICRO-ORGANISMS PROTECT CHILDREN AGAINST GASTROINTESTINAL INFECTIONS
The present invention relates to non-replicating probiotic micro-organisms and their health benefits. In particular, the present invention provides a means to help parents to protect their children from gastro-intestinal infections, in p...
Valerie Petit，Clara Lucia Garcia-Rodenas，M Julita，... - EP
Crystalline forms of a prolyl hydroxylase inhibitor
The present disclosure relates to crystalline solid forms of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid, the process of preparing the forms, and pharmaceutical compositions and methods of use thereof.
C Witschi，JM Park，MD Thompson，... - US
METHODS OF USE AND NUTRITIONAL COMPOSITIONS OF TOUCHI EXTRACT
Disclosed is a method and composition for nutritional compositions containing -glucosidase inhibitors, and more specifically Touchi Extract and its uses in the treatment of many disorders. These disorders include diabetes, hyperlipidemia...
A Falk，Z Roughead，KB Miller，... - EP
Filament based on hyaluronic acid in the form of free acid and method for obtaining it
The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following...
A Domard，L David，F Dupasquier - US
ANALGESIC/ANTIINFLAMMATORY PATCHES FOR TOPICAL USE
Oily analgesic/antiinflammatory patches for topical use which contain diclofenac sodium, pyrrolidone or its derivative, a polyhydric alcohol fatty acid ester and an organic acid in the adhesive drug base. The above patches have the follo...
Y Sasaki，Y Matsumura，M Yamazaki，... - US
DEUTERATED N-ETHYL-N-PHENYL-1,2-DIHYDRO-4-HYDROXY-5-CHLORO-1-METHYL-2-OXOQUINOLINE-3-CARBOXAMIDE, SALTS AND USES THEREOF
The subject invention provides deuterated N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, its salts and uses.
V Piryatinsky，A Laxer
Kinase inhibitors and methods of their use
New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and comp...
Matthew T. Burger，W Han，J Lan，... - US
METHODS OF SCREENING CHEMOTHERAPEUTIC AGENTS AND TREATING CANCER
Methods for selecting chemotherapeutic agents for treating a cancer are provided that include the steps of providing a cancer cell sample having a populati...
PP Claudio，J Valluri
