Therapeutic liposome composition and method of preparation
申请(专利)号:
US19980138480
申请日期:
1998-08-21
公开/公告号:
US6056973A
公开/公告日期:
2000-05-02
申请(专利权)人:
SEQUUS PHARMACEUTICALS, INC.
被引量:
摘要:
Reagents for use in preparing a therapeutic liposome composition sensitized to a target cell are described. The reagents include a liposomal composition composed of pre-formed liposomes having an entrapped therapeutic agent and a plurality of targeting conjugates composed of a lipid, a hydrophilic polymer and a targeting ligand. The therapeutic, target-cell sensitized liposome composition is formed by incubating the liposomal composition with a selected conjugate.
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