Haemoglobin Constant Spring--a chain termination mutant?
摘要：
Haemoglobin Constant Spring is an unusual variant which comprises only 1–2% of the total haemoglobin in heterozygotes. It has α-chains which are 172 residues long instead of the normal 141 and when it is inherited together with an α-thalassaemia gene it gives rise to haemoglobin H disease.
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关键词：
Humans Cyanogen Bromide Tritium Thalassemia Hemoglobinopathies Peptides Trypsin Hemoglobins, Abnormal Amino Acids Chromatography
DOI：
10.1038/234337a0
被引量：
年份：
1971
BMJ
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