DNA gyrase: an enzyme that introduces superhelical turns into DNA
摘要：
Relaxed closed-circular DNA is converted to negatively supercoiled DNA by DNA gyrase. This enzyme has been purified from Escherichia coli cells. The reaction requires ATP and Mg++and is stimulated by spermidine. The enzyme acts equally well on relaxed closed-circular colicin E1, phage λ , and simian virus 40 DNA. The final superhelix density of the DNA can be considerably greater than that found in intracellularly supercoiled DNA.
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DOI：
10.1073/pnas.73.11.3872
被引量：
年份：
1976
掌桥科研
Semantic Scholar
万方医学
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