Compounds
申请(专利)号:
CA19892005132
申请日期:
1989-12-11
公开/公告号:
CA2005132A1
公开/公告日期:
1990-06-13
申请(专利权)人:
BEECHAM GROUP P.L.C.
被引量:
摘要:
A compound of the general formula (I): ##STR1## or a pharmaceutically acceptable ester thereof; or a pharmaceutically acceptable salt thereof, wherein,R.sup.o represents a substituted or unsubstituted aryl group or a substituted or unsubstituted benzofuranyl group,X represents a bond or --O--CH.sub.2 --, R.sup.1 represents a hydrogen atom or a moiety ##STR2## wherein R.sup.o and X are as defined above; R.sup.2 and R.sup.3 independently represent a hydrogen atom or an alkyl group,< P>n represents an integer 1 or 2,Y represents a bond or a moiety --CH.sub.2 --O--, moiety A represents an aryl group, < P>R.sup.4 represents a linking group, and R.sup. 5 represents a substituted or unsubstituted, monocyclic or fused ring heterocyclic group, having up to four heteroatoms in each ring selected from, oxygen, nitrogen and sulphur; provided that R.sup.5 is not N- piperazinyl, N-piperadinyl, N-homopiperadinyl, N-pyrrolidinyl or N- morpholinyl; pharmaceutical compositions containing such compounds and their use in medicine and agriculture.
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