Fluorinated quinoid inhibitor: possible `pure\" arylator predicted by the simple theoretical calculation
摘要：
We report on the fluorinated form of Cpd 5 as a cell growth inhibitor. This compound is 3-fold more potent than the parent Cpd 5 and is predicted, using the semi-empirical AM1 method to be only an arylator of cysteine-containing proteins, without generating reactive oxygen species.We report on the fluorinated form of Cpd 5 as a cell growth inhibitor.
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DOI：
10.1016/j.bmcl.2004.05.009
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年份：
2004
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