Influenza virus neuraminidase: Structure, antibodies, and inhibitors
摘要：
The determination of the 3-dimensional structure of the influenza virus neuraminidase in 1983 has served as a platform for understanding interactions between antibodies and protein antigens, for investigating antigenic variation in influenza viruses, and for devising new inhibitors of the enzyme. That work is reviewed here, together with more recent developments that have resulted in one of the inhibitors entering clinical trials as an anti-influenza virus drug.
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DOI：
10.1002/pro.5560031007
被引量：
年份：
2010
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