Thymocyte apoptosis induced by p53-dependent and independent pathways.
摘要:
Studies the dependence of apoptosis on p53 expression in cells from the thymus cortex. The results show that p53 exerts a significant and dose-dependent effect in the initiation of apoptosis, but only when it is induced by agents that cause DNA-strand breakage; Strategy for the inactivation of the murine p53 gene; Details.
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年份:
1993
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