Tyrosine Kinase Inhibitors
申请(专利)号：
CA20072659582
申请日期：
2007-06-18
公开/公告号：
CA2659582A1
公开/公告日期：
2007-12-27
申请(专利权)人：
MERCK & CO., INC.
关键词：
tyrosine kinase inhibitors and chronic myeloid leukemia (CML) EKB‐569 (pelitinib) – designed, irreversibly inhibiting EGFR and/or ERBB2 KIT inhibitors and stromal tumors of gastrointestinal tract (GIST)
被引量：
摘要：
The present invention relates to 4-indol-3-yl-N-phenylpyrimidin-2-amine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
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