Compositions and methods for the therapy and diagnosis of lung cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode ...
Harlocker, Susan L.，T Wang，CS Bangur，... - US
Cosmetic compositions comprising at least one crosslinked copolymer, at least one insoluble mineral particle and at least one polymer, and uses thereof
Disclosed herein are a cosmetic composition comprising, in a cosmetically acceptable medium, at least one crosslinked copolymer comprising at least one methacrylic acid unit and at least one C 1 -C 4 alkyl acrylate unit, at least one pol...
M Maubru，S Restle，B Perron - US
NUCLEIC ACID CAPABLE OF REGULATING THE PROLIFERATION OF CELL
Provided are an agent for suppressing or promoting cell proliferation, a diagnostic reagent or therapeutic drug for a disease resulting from a cell proliferation abnormality, an agent for inducing apoptosis, an agent for suppressing or p...
H Nakano，T Miyazawa，Y Yamada，... - EP
Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition
A hair-cosmetic composition comprising, in a cosmetically acceptable medium, at least one film-forming gradient copolymer comprising at least two different monomeric residues, and displaying a mass polydispersity index (Ip) less than or ...
Mougin, Nathalie
Piperazine compounds as inhibitors of MMP or TNF
A compound of formula (I) wherein A is a sulfonyl or a carbonyl; R 1 is an optionally substituted aryl, an optionally substituted heterocyclic group, an optionally substituted lower alkyl or an optionally substituted lower alkenyl; R 2 i...
M Neya，H Yamazaki，N Kayakiri，...
Iontophoresis apparatus and method for the diagnosis of tuberculosis
An iontophoresis device includes an active electrode assembly including an active electrode element and at least one active agent reservoir. Active agents include one or more polypeptides, or fusion polypeptides, having antigenic determi...
Steven G. Reed - US
Solid Compositions
The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferab...
B Liepold，T Jung，Peter Hlig，... - WO
2-aminooxazolines as TAAR1 ligands
The invention relates to compounds of formula wherein R 1 , R 2 , and R 3 are as defined herein and to a pharmaceutically suitable acid addition salts thereof for the treatment of CNS disorders.
G Galley，K Groebke Zbinden，R Norcross，... - US
PME-1 as a biomarker to predict and diagnose an increased risk of endometrial cancer and gene silencing of PME-1 to inhibit epithelial to mesenchymal trans...
Disclosed are methods of attenuating activity of the PME-1 gene. siRNAs or shRNAs are used to target against PME-1, thereby reducing the PME-1 mRNA. It is ...
L Rice，M Pusey，E Wandzioch，...
SUPEROXIDE DISMUTASE MIMICS FOR THE TREATMENT OF OCULAR DISORDERS AND DISEASES
The use of SOD mimics particularly pentaazacycle Mn (II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
PG Klimko，RJ Collier，MR Hellberg - US
