MAP kinases in the immune response.
摘要：
MAP kinases are among the most ancient signal transduction pathways and are widely used throughout evolution in many physiological processes. In mammalian species, MAP kinases are involved in all aspects of immune responses, from the initiation phase of innate immunity, to activation of adaptive immunity, and to cell death when immune function is complete. In this review, we summarize recent progress in understanding the function and regulation of MAP kinase pathways in these phases of immune responses.
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关键词：
Animals Humans T-Lymphocytes, Helper-Inducer Intracellular Signaling Peptides and Proteins rac GTP-Binding Proteins Proteins Mitogen-Activated Protein Kinase Kinases MAP Kinase Kinase 3 Mitogen-Activated Protein Kinases JNK Mitogen-Activated Protein Kinases
DOI：
10.1146/annurev.immunol.20.091301.131133
被引量：
年份：
2002
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