Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer.

来自 dx.doi.org

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770

作者：

DK Gardner，M Lane，J Stevens，T Schlenker，WB Schoolcraft

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摘要：

Objective: To determine the relationship between blastocyst score and pregnancy outcome. Design: Retrospective review of blastocyst transfer in an IVF clinic. Setting: Private assisted reproductive technology unit. Patient(s): 107 patients undergoing blastocyst culture and transfer of two embryos. Intervention(s): Culture of all pronucleate embryos in sequential media to the blastocyst stage (day 5), followed by transfer of two blastocysts. Main Outcome Measure(s): Implantation rates, pregnancy rates, and twinning were analyzed. Result(s): When a patient received two top-scoring blastocysts (64% of patients), implantation and pregnancy rates were 70% and 87%, respectively. The twinning rate in this group was 61%. When only one top-quality blastocyst was available for transfer (21% of patients), the implantation and pregnancy rates were 50% and 70%. The twinning rate for this group was 50%. In contrast, when only low-scoring blastocysts were available for transfer (15% of patients), implantation and pregnancy rates were 28% and 44%, and the twinning rate was 29%. No monozygotic twins were observed in this group of patients. Conclusion(s): The ability to transfer one high-scoring blastocyst should lead to pregnancy rates greater than 60%, without the complication of twins.

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关键词：

ART embryo culture implantation IVF viability

DOI：

10.1016/S0015-0282(00)00518-5

被引量：

2873

年份：

2000