Neuraminidase inhibitors for influenza
摘要:
Presents a review article about the use of neuraminidase inhibitors for the treatment of influenza. Threats of an avian influenza pandemic; Scenarios for which vaccination is inadequate and effective antiviral agents would be of importance; Report that antigenic drift in the influenza virus may occur after formulations of the year's vaccine has taken place; Report that influenza vaccine supplies would be inadequate in the course of a pandemic; Claim that antiviral agents are an important part of an approach to epidemic influenza; Drugs that are available for the treatment or prophylaxis of influenza infections, including adamantanes and neuraminidase inhibitors; Clinical trials of the neuraminidase inhibitors zanamivir and oseltamivir; Efficacy of zanamivir and oseltamivir in the prophylaxis of influenza; Report that the development of resistance to neuraminidase inhibitors is very rare; Planning for an avian influenza pandemic.
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DOI:
10.1056/NEJMra050740
被引量:
年份:
2013
































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