Expedient synthesis of 4- O -methylhonokiol via Suzuki–Miyaura cross-coupling

来自 Elsevier

阅读量:

11

作者:

JH KwakYA ChoJY JangSY SeoH LeeJT HongSB HanK LeeYS KwakJK Jung

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摘要:

Concise and practical synthesis of 4- O-methylhonokiol was achieved in 34% overall yield. The key features of our synthesis include chemoselective ortho-mono bromination of phenol as well as biaryl formation via Suzuki–Miyaura cross-coupling, in which bromophenol was reacted with potassium aryltrifluoroborate using Pd(OAc) 2 and RuPhos under microwave conditions.

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DOI:

10.1016/j.tet.2011.09.115

被引量:

28

年份:

2011

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2015
被引量:14

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