Synthesis of the Optically Active Enantiomorphic 2,3-Butanediols1

阅读量:

17

作者:

LJ RubinHA LardyHOL Fischer

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摘要:

The optically active D- and L-2,3-butanediols have been synthesized from the corresponding D- and L-mannitols by a series of unequivocal reactions. The 2,3-isopropylidene derivatives and the di-p-nitrobenzoates of the synthetic butanediols were compared with the same derivatives of the natural, levorotatory butanediol. This proved that the levorotatory butanediol had the D-configuration, the dextrorotatory the L-configuration. The conclusions of previous workers, based on degradative studies, are thus confirmed.

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DOI:

10.1021/ja01122a043

被引量:

86

年份:

1952

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