Highly sensitive amperometric sensor for carbamazepine determination based on electrochemically reduced graphene oxide–single-walled carbon nanotube composite film

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摘要：

We report a highly sensitive amperometric sensor for the determination of carbamazepine (CBZ) at an electrochemically reduced graphene oxide (ERGO) and single walled carbon nanotube (SWCNT) composite film modified glassy carbon electrode (GCE). The π–π stacking interactions between ERGO and SWCNT add good stability to the composite film which was confirmed by UV–visible and FTIR spectroscopy. Compared with SWCNT modified electrode, ERGO–SWCNT composite film modified electrode exhibits a 3.2 fold enhancement in peak current for CBZ oxidation. The proposed sensor detects CBZ as low as 29nM and has a sensitivity of 5.1076μAμM1cm2 in the linear range of 50nM to 3μM. The practicality of this sensor has been evaluated by the determination of CBZ from Tegratol tablets showing good sensitivity and linearity.

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关键词：

Carbamazepine Graphene-SWCNT composite Graphene oxide Electrochemical reduction Amperometry

DOI：

10.1016/j.snb.2012.06.088

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年份：

2012