Hürthle cell and mitochondrion-rich papillary carcinomas of the thyroid gland: an ultrastructural and immunocytochemical study.

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作者：

Sobrinho-sim?es, M. A.，JM Nesland，R Holm，MC Sambade，JV Johannessen

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摘要：

Of 52 consecutive papillary carcinomas of the thyroid, the following cases were included in this study: one Hrthle cell papillary carcinoma, one papillary carcinoma with foci of Hrthle cells, and 10 cases of papillary carcinoma with abundant mitochondria (volumetric density of mitochondria 20%). All cases were studied by light microscopy, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and immunocytochemistry. Our results showed that papillary carcinomas mainly or exclusively composed of Hrthle cells are very rare; that Hrthle cell papillary carcinomas of the thyroid share the biologic characteristics and blend insidiously with the so-called mitochondrion-rich papillary carcinomas; that TEM and SEM can provide useful evidence for achieving the differential diagnosis between Hrthle cell and so-called mitochondrion-rich papillary carcinomas; and that immunocytochemical studies are useless in the aforementioned differential diagnosis.

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关键词：

thyroid Hürthle cell papillary carcinoma electron microscopy immunocytochemistry

DOI：

10.3109/01913128509142147

被引量：

283

年份：

1985