Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus
摘要：
New glycosphingolipids, named agelasphins (<SPAN style="FONT-WEIGHT: bold">1-8</SPAN>), have been isolated by antitumor and immunostimulatory bioassay-guided purification from an extract of a marine sponge, <SPAN style="FONT-STYLE: italic">Agelas mauritianus</SPAN>. Strongly active agents in agelasphins had characteristic α-galactosylceramide structures, the isolation of which from natural products has not previously been reported. The absolute configurations of agelasphins were elucidated by the total synthesis.
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DOI：
10.1016/S0040-4020(01)86991-X
被引量：
年份：
1994
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