Plasma androstenedione levels in women with breast cancer
摘要:
The levels of plasma androstenedione have been measured in 79 normal women, 65 and 61 patients with early breast cancer (Stage I or II) one day before and ten days after mastectomy, respectively, and 69 patients with advanced metastatic disease. There was no significant difference between the mean levels of androstenedione in normal women and subjects with early breast cancer, before mastectomy. However, the general level of androstenedione was significantly subnormal after mastectomy, or in patients with advanced breast cancer. Also there was a significant reduction in the general level of plasma androstenedione associated with mastectomy. In all categories of women the plasma level of androstenedione was highly correlated with the plasma concentrations of dehydroepiandrosterone sulphate and the excretion of urinary 11-deoxy- 17-ketosteroids.
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DOI:
10.1016/0014-2964(77)90198-0
被引量:
年份:
1977
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