The scanning model for translation: an update.
阅读量：
231
摘要：
The small (40S) subunit of eukaryotic ribosomes is believed to bind initially at the capped 5′-end of messenger RNA and then migrate, stopping at the first AUG codon in a favorable context for initiating translation. The first-AUG rule is not absolute, but there are rules for breaking the rule. Some anomalous observations that seemed to contradict the scanning mechanism now appear to be artifacts. A few genuine anomalies remain unexplained.
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关键词：
Animals Humans Ribosomes RNA, Transfer, Amino Acyl Codon Regulatory Sequences, Nucleic Acid Genes, Fungal Models, Biological RNA, Messenger Genes, Viral
DOI：
10.1083/jcb.108.2.229
被引量：
年份：
1989
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