Feasibility of dexmedetomidine in facilitating extubation in the intensive care unit

来自 Wiley

阅读量:

36

作者:

PAA BcpsK KalafatasBT Thompson

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摘要:

Background: Spontaneous breathing trials (SBT) and intermittent mandatory ventilation (IMV) are common techniques utilized to expedite the ventilator weaning process. These techniques often require the reduction and/or discontinuation of sedatives and analgesics. Reducing these medications can lead to agitation and the inability to conduct SBTs or weaning by IMV. Adding dexmedetomidine (dex), a potent alpha-2-adrenergic receptor agonist that possesses sedative, anxiolytic and analgesic effects without causing significant respiratory depression, may facilitate extubation in these patients.

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DOI:

10.1111/j.1365-2710.2008.00883.x

被引量:

166

年份:

2010

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