Pharmacologically Acceptable Salts of Clopidogrel

阅读量:

65

申请(专利)号:

US10590391

申请日期:

20050216

公开/公告号:

US20070249660A1

公开/公告日期:

20071025

申请(专利权)人:

Beat T. Weber Michael Karl Levis Hon Quang Ly

发明人:

Beat T. WeberMK LevisHQ Ly

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被引量:

158

摘要:

The invention relates to polymorphous forms of (+)-(S)-clopidogrel hydrogen bromide, described as polymorphous "form A", polymorphous "form B", polymorphous "form C", polymorphous "form D", polymorphous "form E", and polymorphous "form F", in addition to polymorphous forms of (+)-(S)-clopidogrel napsylate, that are described as polymorphous "form A" and polymorphous "form B" and differ in the X-ray powder diffraction diagrams (XRPD) thereof. The invention also relates to the salts clopidogrel besylate, clopidogrel tosylate and clopidogrel oxalate, and to methods for the production thereof.

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2011
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