Xenobiotic delivery vehicles, method of forming them and method of using them

阅读量:

9

申请(专利)号:

US06/137312

申请日期:

19800404

公开/公告号:

US04298594A

公开/公告日期:

19811103

申请(专利权)人:

ARTHUR D. LITTLE INC.

发明人:

B SearsDW Yesair

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被引量:

63

摘要:

A vehicle suitable for delivering a xenobiotic to a mammalian host to beneficially alter the pharmacodynamics (e.g., plasma kinetics, chemotherapeutic effectiveness, toxicity, oral absorption, tissue distribution, metabolism and the like) of the xenobiotic. The delivery vehicle is in the form of microreservoirs formed of a phospholipid constituent and a phospholipid-immiscible constituent. Xenobiotic binding agents and release agents may be added. Methods for preparing the microreservoirs containing the xenobiotic and for administering a xenobiotic to beneficially alter its pharmacodynamics are disclosed.

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被引量:6

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