Xenobiotic delivery vehicles, method of forming them and method of using them
申请(专利)号:
US06/137312
申请日期:
19800404
公开/公告号:
US04298594A
公开/公告日期:
19811103
申请(专利权)人:
ARTHUR D. LITTLE INC.
被引量:
摘要:
A vehicle suitable for delivering a xenobiotic to a mammalian host to beneficially alter the pharmacodynamics (e.g., plasma kinetics, chemotherapeutic effectiveness, toxicity, oral absorption, tissue distribution, metabolism and the like) of the xenobiotic. The delivery vehicle is in the form of microreservoirs formed of a phospholipid constituent and a phospholipid-immiscible constituent. Xenobiotic binding agents and release agents may be added. Methods for preparing the microreservoirs containing the xenobiotic and for administering a xenobiotic to beneficially alter its pharmacodynamics are disclosed.
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