Gamma hydroxybutyrate in the monkey. IV. Dopaminergic mechanisms

来自 NCBI

阅读量:

20

作者:

OC Snead Rd

展开

摘要:

The electrical seizure activity and trancelike state induced in the rhesus monkey by gamma-hydroxybutyrate (GHB) were abolished by dextroamphetamine. Dextroamphetamine blockade of this neurophysiologic effect was overcome with chlorpromazine, a dopamine receptor blocker. These results suggest that the electroencephalographic (EEG) and behavioral effects of GHB are related to effects on dopaminergic systems. Such a relationship, if substantiated by further studies, might indicate that anticonvulsant drugs used to treat petit mal epilepsy have a dopaminergic mode of action.

展开

DOI:

10.1212/WNL.28.7.643

被引量:

304

年份:

1978

通过文献互助平台发起求助,成功后即可免费获取论文全文。

相似文献

参考文献

引证文献

来源期刊

Neurology
11/1978

引用走势

2010
被引量:25

辅助模式

0

引用

文献可以批量引用啦~
欢迎点我试用!

引用