Comparative molecular neuroanatomy of cloned GABAA receptor subunits in the rat CNS
摘要：
γ-Aminobutyric acidA (GABAA) receptors in the mammalian central nervous system (CNS) are members of a family of ligand-gated ion channels consisting of heterooligomeric glycoprotein complexes in synaptic and extrasynaptic membranes. Although molecular cloning studies have identified 5 subunits (with 40% amino acid homology) and isoforms thereof (70% homology), namely α1–6, β1–4, γ1–3, δ, and ρ, the subunit composition and stoichiometry of native receptors are not known.
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关键词：
receptor heterogeneity receptor composition in situ hybridization histochemistry mRNA rat brain spinal cord
DOI：
10.1002/cne.903260204
被引量：
年份：
1992
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