Low doses of epidural ketamine or neostigmine, but not midazolam, improve morphine analgesia in epidural terminal cancer pain therapy
摘要：
Conclusion: The association of either low-dose epidural ketamine or neostigmine (but not midazolam) to epidural morphine increased the duration of analgesia in the population studied (gt;20 days) compared to the CG and MG (8 to 10 days) when administered in the early stages of terminal cancer pain therapy, without increasing the incidence of adverse effects.
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关键词：
Humans Pain, Intractable Ketamine Neostigmine Midazolam Double-Blind Method Analgesia, Epidural Drug Synergism Adult Aged
DOI：
10.1016/S0952-8180(99)00122-1
被引量：
年份：
1999
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