Applications of Total Synthesis Toward the Discovery of Clinically Useful Anticancer Agents
摘要：
Thistutorial reviewprovides a historical sampling of synthetic efforts undertaken in our laboratory, which have led to the total syntheses of a range of small molecule natural products of potential interest in oncology. It has become evident that natural products, and structures clearly derivable from natural products, have a remarkable record in the treatment of cancer at the clinical level. It is likely that, with the growing power of chemical synthesis, small molecule natural products will play a continuing role in providing lead anticancer compounds.
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关键词：
organic chemistry, review anticarcinogenic activity, anticancer activity general (heterocyclic compounds
DOI：
10.1039/b611967k
被引量：
年份：
2007
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