A Gas Chromatographic Assay for Ketamine in Human Plasma
摘要：
A highly sensitive, quantitative assay procedure for ketamine and two of its metabolites, based upon gas-liquid chromatography of a heptafluorobutyryl derivative, has been developed. No appreciable interference occurred with procaine, atropine, meperidine or promethazine. Anesthetic doses in man (iv) produced ketamine plasma levels above 1 [mu]g/ml, with a biological half-life of 17 min. The presence of the N-dealkylated metabolite of ketamine in human plasma was clearly demonstrated. (C) 1972 American Society of Anesthesiologists, Inc.
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DOI：
10.1097/00000542-197204000-00016
被引量：
年份：
1972
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2010
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