Pad to be installed on gum comprising nonporous layer, adjacent layer retaining medication capable of being liquefied by saliva, semipermeable layer covering second layer and sealed to first layer to form pocket enclosing second layer

阅读量:

23

公开/公告号:

US6319510 B1

公开/公告日期:

Nov 20, 2001

发明人:

A Yates

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被引量:

166

摘要:

The Gum Pad is a laminate composed of: (a) a synthetic base or backing layer which is configured to be held in place on the gingiva (gums) in the mouth; (b) an intermediate, reservoir layer for containing medication therein; and (c) a semi-permeable outer layer facing outwardly toward oral mucosal tissues in the mouth which will allow saliva to enter and dissolve the medication in the reservoir layer into solution and pass the diffused saliva-medication solution outwardly to the oral mucosal tissues. The backing layer is placed on the gum so that the semi-permeable outer layer faces outwardly toward the buccal mucosa. Saliva enters the semi-permeable layer and dissolves the medication in the reservoir layer, then diffuses outwardly through the semi-permeable layer to the mucosal tissues in the mouth where it is readily absorbed into the circulatory system. The Gum Pad can be used for the topical or systemic delivery of a wide range of pharmaceutical and nutritional agents, for the treatment of a variety of human disorders and diseases.

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2004
被引量:17

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