Neighboring Carbon and Hydrogen. XXII. Homoallylic Systems. the Preparation and Behavior of Certain 3,5-Cyclosteroids
Homoallylic systems offer an interesting departure from the more familiar allylic ones. In this connection, 5-cholesten-3β-yl and the related 3,5-cyclocholestan-6β- and 6α-yl derivatives are interesting. In the present work, the prepa...
EM Kosower，S Winstein - 《Journal of the American Chemical Society》
The Effect of Ring Size on the Rate of Acetolysis of the Cycloalkyl p-Toluene and p-Bromobenzenesulfonates1
A number of cycloalkyl tosylates (4-, 5-, 6-, 7-, 8-, 9-, 11-, 12-, 13-, 14-, 15- and 17-ring members) have been synthesized and the rates of acetolysis measured at several temperatures in order to ascertain the effect of ring size on re...
HC Brown，G Ham - 《Journal of the American Chemical Society》
Approaches to the Total Synthesis of Adrenal Steroids.1 V. 4b-Methyl-7- ethylenedioxy-1,2,3,4,4aα,4b,5,6,7,8,10,10a β-dodecahydrophenanthrene-4 β-ol-1-one and Related Tricyclic Derivatives
Publication » Approaches to the Total Synthesis of Adrenal Steroids.1 V. 4b-Methyl-7- ethylenedioxy-1,2,3,4,4aα,4b,5,6,7,8,10,10a β-dodecahydrophenanthrene-4 β-ol-1-one and Related Tricyclic Derivatives.
Poos, G. I.，Arth, G. E.，Beyler, R. E.，... - 《Journal of the American Chemical Society》
CYCLIC POLYOLEFINS. XXXII. CIS- AND TRANS-1, 3-DIPHENYLCYCLOOCTANE
Authentic samples of the two geometric isomers of 1,3-diphenylcyclooctane have been prepared and proved to be identica with the two isomers previously obta...
AC Cope，MR Kinter，RT Keller - 《Journal of the American Chemical Society》
Proximity Effects. VIII. Solvolysis of cis-Cycloöctene Oxide; Synthesis of Alcohols in the Cycloöctane Series1
Summary The complex nature of the challenge posed by state鈥搒ociety relations to the realisation of citizenship rights in the poorer countries of the worl...
AC Cope，AH Keough，PE Peterson，... - 《Journal of the American Chemical Society》
Proximity effects. VI. Stereospecific syntheses of cis- and trans- 1,4-cycloöctanediols
1,4-Epoxycyclooctane (I) has been prepared by a sequence of reactions beginning with 3,6-epoxycycloheptanecarbonitrile (II and III, cis and trans isomers). Each of the nitriles was hydrogenated to a single primary amine, but in the synth...
A.C. Cope - 《Journal of the American Chemical Society》
Proximity Effects. XIII. Stereochemistry of the cis-Bicyclo[3.3.0]octan-2-ols
The known epimeric cis-bicyclo[3.3.0]octan-2-ols have been stereochemically related to the two epimeric cis-bicyclo [3.3.0]-octane-2-carboxylic acids. This has been achieved by the perbenzoic acid cleavage of the two methyl ketones prepa...
AC Cope，M Brown，HE Petree - 《Journal of the American Chemical Society》
Proximity Effects. IV. Reaction of Cycloctene Dibromide with Silver Acetate1
The reaction of cycloctene dibromide with silver acetate in dry acetic acid has been shown to yield 3-cycloocten-1-yl acetate, 4-cycloocten-1-yl acetate, cis-1,4-cyclooctanediol diacetate, trans-1,4-cyclooctanediol diacetate and only a s...
AC Cope，GW Wood - 《Journal of the American Chemical Society》
Addition of Formic Acid to Olefinic Compounds. I. Monolefinic Compounds2
Thirty-one acyloxy or aryloxy esters prepared from hydroxystearic acids have been evaluated as plasticizers for a vinyl chloride-vinyl acetate copolymer (95:5). Many of them were found to be primary plasticizers, having outstanding low-t...
HB Knight，RE Koos，D Swern - 《Journal of the American Chemical Society》
Neighboring Carbon and Hydrogen. XXIII. Homoallylic Systems. 3,5-Cyclocholestan-6β-yl Chloride 1
By taking advantage of the reactivity associated with the i-steryl structure in ionization reactions and the mediating action of the solvent ether upon hydrogen chloride, 3,5-cyclocholestan-6β-yl chloride has been prepared from 3,5-cycl...
EM Kosower，S Winstein - 《Journal of the American Chemical Society》
