New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor

阅读量:

12

申请(专利)号:

AU7823894

申请日期:

19940829

公开/公告号:

AU7823894A

公开/公告日期:

19950321

申请(专利权)人:

VRIJE UNIVERSITEIT

被引量:

77

摘要:

The invention relates to new imidazole derivatives of formula (I) having agonistic and antagonistic activity on the histamine H3-receptor. More in particular the invention concerns 4- and 5-substituted aminoalkyl imidazoles and their derivatives. The invention further relates to the synthesis of these compounds, pharmaceutical compositions comprising the said compounds or pharmacological salts thereof, and the use of the compounds as agents having biological activity on the histamine H3-receptor or for the preparation of a pharmaceutical composition.

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