A facile synthesis of novel benzofuran-2-yl(9-methyl-9H-carbazol-3-yl)methanones
摘要:
A facile synthesis of hitherto unreported benzofuran-2-yl(9-methyl-9 H -carbazol-3-yl)methanones ( 3a – l ) is described. The synthesis mainly relies on the ultrasound-assisted Rap–Stoermer reaction of 3-chloroacetyl-9-methyl-9 H -carbazole ( 1 ) with a variety of salicylaldehydes, as well as 2-hydroxy-1-naphthaldehyde ( 2 ) in CH 3 CN, with the presence of PEG-400 as a catalyst. This procedure offers easy access to benzofuran-2-yl(carbazolyl)methanone derivatives in a short reaction time and the products are achieved in good yields.
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DOI:
10.1007/s11164-012-0513-1
被引量:
年份:
2012
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