Catalyst–Substrate Coimmobilization: A Strategy for Catalysts Discovery in Split‐and‐Mix Libraries

来自 Wiley

阅读量:

25

作者:

P KrattigerC MccarthyA PfaltzH Wennemers

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摘要:

Potentially applicable to any bimolecular reaction: A new method for the discovery of catalysts among the members of split‐and‐mix libraries is described. A reaction partner (A) is immobilized along with each library member (the potential catalyst) on the same bead. The reaction partner B is labeled with a dye, thus a reaction between A and B is easily visualized through the attachment of the marker to the beads that carry the active catalyst.

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DOI:

10.1002/anie.200250422

被引量:

151

年份:

2002

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