摘要：

Suppressors are genes which suppress the expression of mutant phenotypes. The suppressors can be considered to be mutant genes themselves since they are generally not found in the wild type strains but are obtained by selecting for revertants of the mutant phenotype. A revertant arising by a mutation other than a base change in the original mutant codon carries a suppressor. If the new event occurred at another site within the original mutant gene, it is called by some an intra-locus suppressor. However, in our view this is a misuse of the term suppressor which originated as a designation for those mutations occurring in some other gene, the suppressor gene, and which now must be defined as an external suppressor. The external or extra-locus suppressors can be further classified as being either functional suppressors or informational suppressors.

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