Asymmetric Catalysis with Chiral Lewis Bases
摘要：
Catalytic, asymmetric aldol additions have come to the forefront of synthetic methodology due to both the synthetic utility of the products and the challenge of designing such a transformation. 1 There are now a number of reports concerning the addition of silyl enol ethers or silyl ketene acetals to aldehydes using chiral Lewis acids that proceed with good-to-high enantioselectivity. 2 Despite the advantages of chiral Lewis acid catalysis, an asymmetric catalytic aldol reaction with the generality and selectivity of the well known stoichiometric methods still remains to be developed. We envisioned the possibility of devising a new reaction that uses chiral Lewis base catalysis, that is, activation of the nucleophile, Scheme 1. 3 , 4
展开
DOI：
10.1351/pac199870081469
被引量：
年份：
1998
De Gruyter
Springer
De Gruyter
(全网免费下载)
国家科技图书文献中心
(权威机构)
doi.org
查看更多
dx.doi.org
ResearchGate
ResearchGate
(全网免费下载)
EBSCO
old.iupac.org
(全网免费下载)
www2.lsdiv.harvard.edu
(全网免费下载)
media.iupac.org
(全网免费下载)
evans.rc.fas.harvard.edu
(全网免费下载)
iupac.org
(全网免费下载)
list.iupac.org
(全网免费下载)
moureu.iupac.org
(全网免费下载)
iupac.org
(全网免费下载)
iupac.org
De Gruyter
(全网免费下载)
ResearchGate
(全网免费下载)
evans.rc.fas.harvard.edu
(全网免费下载)
iupac.org
(全网免费下载)
list.iupac.org
(全网免费下载)
iupac.org
(全网免费下载)
moureu.iupac.org
(全网免费下载)
media.iupac.org
(全网免费下载)
old.iupac.org
(全网免费下载)
www2.lsdiv.harvard.edu
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
