Oligodeoxynucleotide and its use to induce an immune response
申请(专利)号：
US20020068160
申请日期：
2002-02-06
公开/公告号：
US2003060440A1
公开/公告日期：
2003-03-27
申请(专利权)人：
KLINMAN DENNIS;VERTHELYI DANIELA;ISHII KEN;MOND JAMES J.;GURSEL MAYDA
被引量：
摘要：
D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula: 5′XXXPuPyCpGPuPyXXX(W)(G)-3′ wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10. Methods of using these oligodeoxynucleotides to induce an immune response are provided.
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