Rate of Fixation of Nucleotide Substitutions in Evolution
摘要：
Nucleotide sequences of rodents and of artiodactyls have been compared by DNA/DNA duplex formation. The rate of evolution in terms of fixation of nucleotide substitutions inferred from non-repeated artiodactyl DNAs is three times greater than that inferred from comparative amino-acid sequence of theandchains of haemoglobin from these same organisms. The initial rate of nucleotide sequence variation among rodents is ten-fold higher than that among artiodactyls when divergence time is estimated in years. This difference diminishes if generations, rather than years, represent the appropriate interval of evolutionary divergence.
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DOI：
10.1038/224149a0
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