摘要：

Objective To explore the effect of the various HPV genotypes on cervical neoplasia.Methods The HPV genotypes in cervical of 476 women were examined with hybridization.238 women had cervical biopsy and were classified as three groups according to the histological diagnosis:(1)Normal group,43 cases;(2)Low grade squmaous intraepithelial lesion LSIL group,152 cases;(3)High grae squmaous intraepithelial lesion HILS group,43 cases.Results Positive rate of HPV in cervical carcinoma,HSIL,LSIL and normal groups respectively was 100%,90.9%,67.7%,and 48.6%.There was significant difference between HSIL group and other two groups(P[WTBZ]0.001).The patients with cervical neoplasia had multiple HPV infection.Conclusion The study shows that the infection of HPV-52,26,51,56,68,CP8304,11 often exists in women suffered from cervical neoplasia.The infection of HPV-16,52,58,31,CP8304,33,18 develops into cervical carcinoma more easily.The women with cervical carcinoma maybe have multiple HPV infection.

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